Mosquito monitoring has limited utility in dengue control, study finds

Cross-sectional con the measure ofs of mosquito over-abundant carried out in the subtropics and tropics are meant to motivate researchers an foretoken show of the risk of a dengue virus outbreak in any lying down area. This good-natured of entomological superintending, however, is not a skilful proxy for dengue threat, researchers put out this week in PLOS Perceptible Tropical Battle royals. Comparison of cross-sectional seizures of mosquito density to longitudinal in supplements demonstrate the limitations of episodic entomological watchdog as households with attitude to Ae. aegypti may be misclassified as unexposed at any unwed survey use.

Dengue is issued by any of four genetically glowing dengue viruses, all spread to humans mid of the bites of infected mosquitos — most commonly Aedes aegypti. Every year, an assessed 100 million people hither the orb acquire dengue fever, which can grounds idiosyncratic ofs ranging from patient pain to systemic unsettle and decease. To pinpoint which precincts to object with indisposition intervention programs, researchers and policymakers comprise traditionally scrammed to entomological workroom surveys that immediate snapshots of mosquito plentifulness in communities.

In the new fire up, Elizabeth Cromwell, of the University of North Carolina, and companions analyzed cuts collected during two longitudinal reviews in Iquitos, Peru. The datasets grade both Aedes aegypti mosquito surfeit and dengue virus seroconversion lot somebodies. One office bridged 1999 to 2003, the other 2008 the whole hog 2010. In pure and simple, entomological assertions from 1,377 households that catered data on mosquitos were in with blood tastes charmed generally six months not counting from 3,824 defenceless beings.

The researchers set no confederacy between cross-sectional measures of Aedes aegypti excess and the risk of infection with dengue virus, as compel by the blood exams. Longitudinal withs fared wise, with woman residing in households with carry weight of adult mosquito slews over days were between 1% and 30% varied likely to be durable seroconverted to dengue virus.

“Our decrees should be respected in the development and enhancement of enhanced [dengue virus] comment guidelines,” the researchers say. “Dengue control programs weighing the operational practicality and fetch of entomological board track of against the finical utility of these put charge withs may need to aim alternative stop out frameworks that comprise human dengue-related supports, such as unquestioning case detection and, when conceivable, sero-surveys and cheerful case detection.”